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You Shang Selected Research

methyl ester 5(S),6(R)-7-trihydroxyheptanoic acid

4/2019BML-111 accelerates the resolution of inflammation by modulating the Nrf2/HO-1 and NF-κB pathways in rats with ventilator-induced lung injury.
12/2018BML-111 suppresses TGF-β1-induced lung fibroblast activation in vitro and decreases experimental pulmonary fibrosis in vivo.
1/2018BML-111 Reduces Neuroinflammation and Cognitive Impairment in Mice With Sepsis via the SIRT1/NF-κB Signaling Pathway.
2/2016BML-111 attenuates acute lung injury in endotoxemic mice.
4/2014BML-111, a lipoxin receptor agonist, attenuates ventilator-induced lung injury in rats.
8/2013BML-111 attenuates hemorrhagic shock-induced acute lung injury through inhibiting activation of mitogen-activated protein kinase pathway in rats.
7/2012Lipoxin receptor agonist, may be a potential treatment for hemorrhagic shock-induced acute lung injury.
7/2012BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats.

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You Shang Research Topics

Disease

23COVID-19
03/2021 - 01/2020
17Acute Lung Injury
04/2020 - 01/2006
14Inflammation (Inflammations)
03/2021 - 04/2010
10Critical Illness (Critically Ill)
08/2021 - 10/2015
10Lung Injury
04/2019 - 01/2006
8Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
03/2021 - 10/2015
7Sepsis (Septicemia)
01/2022 - 09/2016
7Reperfusion Injury
12/2021 - 04/2010
7Ischemia
01/2019 - 06/2009
6Pneumonia (Pneumonitis)
01/2021 - 04/2009
6Brain Ischemia (Cerebral Ischemia)
03/2016 - 04/2010
5Ventilator-Induced Lung Injury
01/2022 - 02/2007
5Pulmonary Edema
04/2020 - 12/2016
5Stroke (Strokes)
01/2020 - 03/2012
4Respiratory Insufficiency (Respiratory Failure)
11/2022 - 01/2020
4Neuroinflammatory Diseases
12/2021 - 08/2012
4Endotoxemia
12/2021 - 06/2009
4Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2021 - 11/2015
4Wounds and Injuries (Trauma)
05/2018 - 04/2008
4Neurodegenerative Diseases (Neurodegenerative Disease)
01/2017 - 06/2007
3Hypoxia (Hypoxemia)
11/2022 - 05/2018
3Infections
05/2022 - 01/2017
3Cognitive Dysfunction
12/2021 - 01/2018
3Septic Shock (Toxic Shock Syndrome)
04/2021 - 10/2010
3Fibrosis (Cirrhosis)
01/2021 - 11/2015
3Thrombocytopenia (Thrombopenia)
01/2021 - 01/2020
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2018 - 10/2010
3Necrosis
05/2014 - 04/2009
3Hemorrhagic Shock
08/2013 - 10/2010
2Hemorrhage
05/2022 - 01/2020
2Myocardial Ischemia (Ischemic Heart Diseases)
12/2021 - 01/2021
2Pain (Aches)
08/2021 - 02/2016
2Body Weight (Weight, Body)
01/2021 - 02/2016
2Respiratory Hypersensitivity
01/2020 - 05/2018
2Ischemic Stroke
01/2019 - 09/2015
2Nervous System Diseases (Neurological Disorders)
10/2018 - 01/2017
2Infarction (Infarctions)
03/2016 - 09/2015
2Brain Edema (Cerebral Edema)
09/2015 - 03/2012
2Hyperoxia
07/2009 - 04/2009
1Bradycardia
11/2022
1Hypotension (Low Blood Pressure)
11/2022
1Splenomegaly
12/2021

Drug/Important Bio-Agent (IBA)

13CytokinesIBA
01/2022 - 02/2007
12Proteins (Proteins, Gene)FDA Link
12/2021 - 01/2006
9LipoxinsIBA
02/2016 - 04/2010
8LipopolysaccharidesIBA
12/2021 - 01/2006
8methyl ester 5(S),6(R)-7-trihydroxyheptanoic acidIBA
04/2019 - 07/2012
6LipidsIBA
07/2020 - 08/2012
5Death-Associated Protein KinasesIBA
01/2022 - 02/2015
57,14- dihydroxydocosa- 4,8,10,12,16,19- hexaenoic acidIBA
12/2016 - 07/2014
5ErythropoietinFDA Link
07/2009 - 06/2007
4Biomarkers (Surrogate Marker)IBA
04/2021 - 09/2016
4Bleomycin (Blenoxane)FDA LinkGeneric
01/2021 - 06/2009
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020 - 04/2009
4lipoxin A4IBA
01/2018 - 04/2010
4salicylhydroxamic acid (SHAM)IBA
08/2013 - 01/2006
3EndotoxinsIBA
12/2021 - 01/2006
3fibrin fragment D (D-dimer)IBA
03/2021 - 01/2020
3Oxygen (Dioxygen)IBA
03/2021 - 01/2018
3InflammasomesIBA
04/2020 - 01/2017
3Interleukin-6 (Interleukin 6)IBA
01/2020 - 04/2014
3InterleukinsIBA
01/2020 - 04/2014
3triphenyltetrazoliumIBA
03/2016 - 03/2012
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2021 - 08/2012
2Analgesics (Analgesic Drugs)IBA
08/2021 - 02/2016
2Immunoglobulin M (IgM)IBA
01/2021 - 12/2020
2Immunoglobulin G (IgG)IBA
01/2021 - 12/2020
2Valproic Acid (Depakote)FDA LinkGeneric
01/2021 - 10/2010
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2021 - 01/2020
2Indicators and Reagents (Reagents)IBA
01/2021 - 12/2020
2AntibodiesIBA
12/2020 - 12/2020
2HMGB1 Protein (HMG1)IBA
04/2020 - 01/2020
2IsofluraneFDA LinkGeneric
01/2020 - 12/2019
2Local AnestheticsIBA
01/2019 - 10/2018
210,17- dihydroxydocosa- 4,7,11,13,15,19- hexaenoic acidIBA
05/2018 - 01/2017
2Phosphotransferases (Kinase)IBA
01/2018 - 11/2015
2Mitogen-Activated Protein KinasesIBA
01/2018 - 08/2013
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2018 - 08/2011
2Evans Blue (Blue, Evans)FDA Link
12/2016 - 03/2012
2Peroxidase (Myeloperoxidase)IBA
07/2012 - 04/2009
2EstersIBA
10/2010 - 04/2010
2Neuroprotective AgentsIBA
10/2010 - 04/2010
2NF-kappa B (NF-kB)IBA
06/2009 - 04/2009
1remimazolamIBA
11/2022
1Hypnotics and Sedatives (Sedatives)IBA
11/2022
13-(2,4-dimethoxybenzylidene)anabaseineIBA
01/2022
1Brain-Derived Neurotrophic Factor (BDNF)IBA
12/2021
1Atrial Natriuretic Factor (ANF)IBA
12/2021
1Prostaglandins FIBA
12/2021
1ArgonIBA
12/2021

Therapy/Procedure

9Artificial Respiration (Mechanical Ventilation)
01/2021 - 04/2014
5Therapeutics
08/2021 - 10/2019
4Extracorporeal Membrane Oxygenation
05/2022 - 01/2020
3Tracheostomy
01/2021 - 01/2020
3Critical Care (Surgical Intensive Care)
06/2020 - 01/2020
2Cannula
05/2022 - 01/2020
2Anesthesia
01/2020 - 01/2019
2Punctures
12/2019 - 01/2017
2Ligation
12/2019 - 01/2017
2Resuscitation
08/2013 - 07/2012